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dc.contributor.authorSola Rodríguez, Sergio
dc.contributor.authorVargas Hitos, José Antonio
dc.contributor.authorGavilán Carrera, Blanca
dc.contributor.authorRosales Castillo, Antonio
dc.contributor.authorSabio, José Mario
dc.contributor.authorHernández Martínez, Alba
dc.contributor.authorMartínez Rosales, Elena
dc.contributor.authorOrtego Centeno, Norberto
dc.contributor.authorSoriano Maldonado, Alberto
dc.date.accessioned2021-05-03T08:40:36Z
dc.date.available2021-05-03T08:40:36Z
dc.date.issued2021-04-27
dc.identifier.issn1660-4601
dc.identifier.urihttp://hdl.handle.net/10835/10620
dc.description.abstractThis study aimed to examine the association of relative handgrip strength (rHGS) with cardiometabolic disease risk factors in women with systemic lupus erythematosus (SLE). Methods: Seventy-seven women with SLE (mean age 43.2, SD 13.8) and clinical stability during the previous six months were included. Handgrip strength was assessed with a digital dynamometer and rHGS was defined as absolute handgrip strength (aHGS) divided by body mass index (BMI). We measured blood pressure, markers of lipid and glucose metabolism, inflammation (high sensitivity C-reactive protein [hs-CRP]), arterial stiffness (pulse wave velocity [PWV]), and renal function. A clustered cardiometabolic risk index (z-score) was computed. Results: Pearson′s bivariate correlations revealed that higher rHGS was associated with lower systolic blood pressure (SBP), triglycerides, hs-CRP, PWV, and lower clustered cardiometabolic risk (rrange = from −0.43 to −0.23; all p < 0.05). Multivariable linear regression analyses adjusted for age, disease activity (SLEDAI), and accrual damage (SDI) confirmed these results (all p < 0.05) except for triglycerides. Conclusions: The findings suggest that higher rHGS is significantly associated with lower cardiometabolic risk in women with SLE.es_ES
dc.language.isoenes_ES
dc.publisherMDPIes_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectautoimmune diseasees_ES
dc.subjectcardiovascular riskes_ES
dc.subjectmuscle strengthes_ES
dc.subjectbody mass indexes_ES
dc.subjectmetabolismes_ES
dc.subjectcardiovascular diseasees_ES
dc.subjectlupuses_ES
dc.subjectrisk factorses_ES
dc.titleRelative Handgrip Strength as Marker of Cardiometabolic Risk in Women with Systemic Lupus Erythematosuses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://www.mdpi.com/1660-4601/18/9/4630es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doihttps://doi.org/10.3390/ijerph18094630


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional