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dc.contributor.authorLópez Palmero, Serafín
dc.contributor.authorLópez Zúñiga, Miguel Angel
dc.contributor.authorRodríguez Martínez, Virginia
dc.contributor.authorReyes Parrilla, Raul
dc.contributor.authorAlguacil Muñoz, Ana Maria
dc.contributor.authorSánchez-Yebra Romera, Waldo
dc.contributor.authorMartín Rico, Patricia
dc.contributor.authorPoquet Catalá, Inmaculada
dc.contributor.authorJiménez Guardiola, Carlos
dc.contributor.authorDel Pozo Pérez, Alfonso
dc.contributor.authorLobato Cano, Ruben
dc.contributor.authorLazo Torres, Ana Maria
dc.contributor.authorLópez Martínez, Gines
dc.contributor.authorDíez García, Luis Felipe
dc.contributor.authorParrón Carreño, Tesifón 
dc.date.accessioned2022-06-29T15:55:21Z
dc.date.available2022-06-29T15:55:21Z
dc.date.issued2022-06-23
dc.identifier.issn2077-0383
dc.identifier.urihttp://hdl.handle.net/10835/13866
dc.description.abstractBackground: In general, transthoracic echocardiography (TTE) is the first diagnostic test used for patients with bacteremia or candidemia and clinical signs of Infective Endocarditis (IE). Point-of-care ultrasound (POCUS) may be used in addition to physical examination for the detection of structural heart disease and valve abnormalities. Objective: To determine the diagnostic accuracy of POCUS for the detection of signs suggestive of IE, including vegetation, valvular regurgitation, structural heart disease, hepatomegaly, splenomegaly and septic embolisms, in patients with bacteremia or candidemia. Design: Observational, cross-sectional, multicenter study using convenience sampling. Setting: Six Spanish academic hospitals. Patients: Adult patients with bacteremia or candidemia between 1 February 2018 and 31 December 2020. Measurements: The reference test, to evaluate vegetation, valvular regurgitation and structural heart disease, was transesophageal echocardiography (TEE). For patients who did not undergo TEE, transthoracic echocardiography (TTE) was considered the reference test. POCUS was performed by internists, while conventional echocardiography procedures were performed by cardiologists. Results: In 258 patients, for the detection of valvular vegetation, POCUS had sensitivity, specificity, and positive and negative predictive values of 77%, 94%, 82% and 92%, respectively. For valvular regurgitation (more than mild), sensitivity was ≥76% and specificity ≥85%. Sensitivity values for the detection of hepatomegaly and splenomegaly were 92% and 92%, respectively, while those for specificity were 96% and 98%. Conclusion: POCUS could be a valuable tool, as a complement to physical examination, at the hospital bedside for patients with bacteremia or candidemia, helping to identify signs suggestive of IE.es_ES
dc.language.isoenes_ES
dc.publisherMDPIes_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectpoint-of-care ultrasound (POCUS)es_ES
dc.subjectbacteremiaes_ES
dc.subjectcandidemiaes_ES
dc.subjectinfective endocarditises_ES
dc.titlePoint-of-Care Ultrasound (POCUS) as an Extension of the Physical Examination in Patients with Bacteremia or Candidemiaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://www.mdpi.com/2077-0383/11/13/3636es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.3390/jcm11133636


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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