Effective method for a graphene oxide with impressive selectivity in carboxyl groups
MetadataShow full item record
Author/sRodríguez Pastor, Iluminada; López-Pérez, Adelia; Romero-Sanchez, Maria Dolores; Perez, Juana María; Fernandez De Las Nieves, Ignacio; [et al.]
The development of new applications of graphene oxide in the biomedical field requires the covalent bonding of bioactive molecules to a sheet skeleton. Obtaining a large carboxyl group population over the surface is one of the main targets, as carboxyl group concentration in conventional graphene oxide is low among a majority of non-useful sp3-C-based functionalities. In the present work, we propose a selective method that yields an impressive increase in carboxyl group population using single-layer, thermally reduced graphene oxide as a precursor in a conventional Hummers–Offemann reaction. When starting with a reduced graphene oxide with no interlayer registry, sulfuric acid cannot form a graphite intercalated compound. Then, potassium permanganate attacks in in-plane (vacancies or holes) structural defects, which are numerous over a thermally reduced graphene oxide, as well as in edges, yielding majorly carboxyl groups without sheet cutting and unzipping, as no carbon dot formation ...
reduced graphene oxide
graphite intercalated compound