Placido-based indices of corneal irregularity
Identifiers
URI: http://hdl.handle.net/10835/5615
ISSN: 1040-5488
DOI: http://dx.doi.org/10.1097/OPX.0b013e3182279ff8
ISSN: 1040-5488
DOI: http://dx.doi.org/10.1097/OPX.0b013e3182279ff8
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Ramos López, DaríoDate
2011Abstract
Purpose:
To construct a set of metrics computed from the raw keratoscopic data collected by any
Placido corneal topographer. These indices that measure the irregularity of the anterior
corneal surface are computed directly from the image of the mires reflected on the
cornea, which is the most primary data possible. Besides the high sensitivity and
specificity, this approach allows bypassing the surface or curvature reconstruction step
that is currently performed by the software of any commercial Placido topographer.
Methods:
Several basic indices are proposed in order to detect irregularities on the anterior
surface of the cornea, via analyzing some geometric and mathematical properties of
the mires. These individual primary indices are built in a natural and intuitive way
directly from the displacement of the digitized images of the rings reflected on the
cornea. Additionally, compound indices are proposed (such as the generalized linear
model or the classification tree...