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dc.contributor.authorGarrido Cárdenas, José Antonio
dc.contributor.authorGarcía Maroto, Federico
dc.contributor.authorÁlvarez Bermejo, José Antonio
dc.contributor.authorManzano Agugliaro, Francisco
dc.date.accessioned2020-01-16T09:08:28Z
dc.date.available2020-01-16T09:08:28Z
dc.date.issued2017-03-14
dc.identifier.issn1424-8220
dc.identifier.urihttp://hdl.handle.net/10835/7339
dc.description.abstractThe first sequencing of a complete genome was published forty years ago by the double Nobel Prize in Chemistry winner Frederick Sanger. That corresponded to the small sized genome of a bacteriophage, but since then there have been many complex organisms whose DNA have been sequenced. This was possible thanks to continuous advances in the fields of biochemistry and molecular genetics, but also in other areas such as nanotechnology and computing. Nowadays, sequencing sensors based on genetic material have little to do with those used by Sanger. The emergence of mass sequencing sensors, or new generation sequencing (NGS) meant a quantitative leap both in the volume of genetic material that was able to be sequenced in each trial, as well as in the time per run and its cost. One can envisage that incoming technologies, already known as fourth generation sequencing, will continue to cheapen the trials by increasing DNA reading lengths in each run. All of this would be impossible without sensors and detection systems becoming smaller and more precise. This article provides a comprehensive overview on sensors for DNA sequencing developed within the last 40 years.es_ES
dc.language.isoenes_ES
dc.publisherMDPIes_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectDNA sequencinges_ES
dc.subjectnext generation sequencing (NGS)es_ES
dc.subjectpyrosequencinges_ES
dc.subjectfluorescencees_ES
dc.subjectsemiconductores_ES
dc.subjectnanoporees_ES
dc.titleDNA Sequencing Sensors: An Overviewes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://www.mdpi.com/1424-8220/17/3/588es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional