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dc.contributor.authorMartínez Rosales, Elena
dc.contributor.authorSola Rodríguez, Sergio
dc.contributor.authorVargas Hitos, José Antonio
dc.contributor.authorGavilán Carrera, Blanca
dc.contributor.authorRosales-Castillo, Antonio
dc.contributor.authorHernández-Martínez, Alba
dc.contributor.authorArtero, Enrique G.
dc.contributor.authorSabio, José Mario
dc.contributor.authorSoriano-Maldonado, Alberto
dc.date.accessioned2021-01-11T11:40:54Z
dc.date.available2021-01-11T11:40:54Z
dc.date.issued2020-12-18
dc.identifier.issn1660-4601
dc.identifier.urihttp://hdl.handle.net/10835/9283
dc.description.abstractAbnormal heart rate variability (HRV) has been observed in patients with systemic lupus erythematosus (SLE). In a combined cross-sectional and interventional study approach, we investigated the association of HRV with inflammation and oxidative stress markers, patient-reported outcomes, and the effect of 12 weeks of aerobic exercise in HRV. Fifty-five women with SLE (mean age 43.5 ± 14.0 years) were assigned to either aerobic exercise (n = 26) or usual care (n = 29) in a non-randomized trial. HRV was assessed using a heart rate monitor during 10 min, inflammatory and oxidative stress markers were obtained, psychological stress (Perceived Stress Scale), sleep quality (Pittsburg Sleep Quality Index), fatigue (Multidimensional Fatigue Inventory), depressive symptoms (Beck Depression Inventory), and quality of life (36-item Short-Form Health Survey) were also assessed. Low frequency to high frequency power (LFHF) ratio was associated with physical fatigue (p = 0.019). Sample entropy was inversely associated with high-sensitivity C-reactive protein (p = 0.014) and myeloperoxidase (p = 0.007). There were no significant between-group differences in the changes in HRV derived parameters after the exercise intervention. High-sensitivity C-reactive protein and myeloperoxidase were negatively related to sample entropy and physical fatigue was positively related to LFHF ratio. However, an exercise intervention of 12 weeks of aerobic training did not produce any changes in HRV derived parameters in women with SLE in comparison to a control group.es_ES
dc.language.isoenes_ES
dc.publisherMDPIes_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectautonomic nervous systemes_ES
dc.subjectexercisees_ES
dc.subjectinflammationes_ES
dc.subjectfatiguees_ES
dc.subjectrheumatic diseasees_ES
dc.titleHeart Rate Variability in Women with Systemic Lupus Erythematosus: Association with Health-Related Parameters and Effects of Aerobic Exercisees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://www.mdpi.com/1660-4601/17/24/9501es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional