The beneficial effect of statins treatment by stroke subtype
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URI: http://hdl.handle.net/10835/15777
DOI: 10.1111/j.1468-1331.2008.02370.x
DOI: 10.1111/j.1468-1331.2008.02370.x
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Martínez Sánchez, Patricia; Rivera Ordóñez, Carlos; Fuentes, Blanca; Ortega Casarrubios, María Ángeles; Idrovo, Luis; [et al.]Fecha
2009-01-01Resumen
Background and purpose: Statins have shown some protective effect after ischaemic
stroke in observational studies. However, this effect has never been assessed by etiological subtypes. Methods: Observational study using data from the Stroke Unit Data
Bank from consecutive patients with cerebral infarction. Variables analyzed: demographic data, cardiovascular risk factors, treatment with statins at stroke onset, stroke
severity, stroke subtype, in-hospital complications, length of stay, and functional
status at discharge (modified Rankin Scale). Results: A total of 2742 patients were
included, 1539 were men. Mean age was 69.17 years (SD 12.19). Of these, 281 patients
(10.2%) were receiving statins when admitted. The logistic regression analyses showed
that previous treatment with statins was an independent predictor for better outcome
at discharge among all strokes (OR, 2.08; 95% CI, 1.39 to 3.1) as well as for the
atherothrombotic (OR, 2.79; 95% CI, 1.33 to 5.84) and lacunar s...
Palabra/s clave
acute stroke, atherothrombotic infarction, lacunar infarction, outcome, statins