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dc.contributor.authorÁlvarez, Roberto
dc.contributor.authorDe la Casa, Luis G.
dc.contributor.authorSánchez, Pilar
dc.date.accessioned2011-07-13T11:52:01Z
dc.date.available2011-07-13T11:52:01Z
dc.date.issued2003-12
dc.identifier.citationInternational Journal of Psychology and Psychological Therapy, 3(2), 251-266es_ES
dc.identifier.issn1577-7057
dc.identifier.urihttp://hdl.handle.net/10835/89
dc.description.abstractIn schizophrenia, attentional processes may be altered and become the basis of another symptomatology such as delirium and hallucinations. One of the experimental approaches to the study of attentional processes employs the phenomenon of latent inhibition. Behaviourally, latent inhibition is expressed as a delay or difficulty in learning the relationship between stimuli due to prior experience of the subject with one of the inconsequential stimuli. This learning phenomenon fulfils an adaptive function that enables the organism to release attention from irrelevant stimuli. Schizophrenics do not show this latent inhibition effect due to attentional alterations, that is, they have selective attention difficulties. Clinical data coincide with results obtained from both animals and normal subjects and with data from psychopharmacological studies. Most of the studies show that the dopaminergic system plays an important role in latent inhibition and therefore would support the dopaminergic hypothesis of schizophrenia. Furthermore, latent inhibition is used as a model to evaluate the mechanisms of antipsychotic drug action, as well as for the study of the aetiology of schizophrenia. Finally, latent inhibition opens a line of research in cognitive inhibition processes in schizotypy and the possibility of studying other psychopathological disorders. The model proposed is based on experimental, neurochemical and clinical premises that make it a promising topic of future for research.es_ES
dc.language.isoenes_ES
dc.subjectlatent inhibitiones_ES
dc.subjectschizophreniaes_ES
dc.subjectselective attentiones_ES
dc.subjectantipsychotic drugses_ES
dc.titleLatent inhibition as a Model of Schizophrenia: from Learning to Psychopathologyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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