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Relative Handgrip Strength as Marker of Cardiometabolic Risk in Women with Systemic Lupus Erythematosus
dc.contributor.author | Sola Rodríguez, Sergio | |
dc.contributor.author | Vargas Hitos, José Antonio | |
dc.contributor.author | Gavilán Carrera, Blanca | |
dc.contributor.author | Rosales Castillo, Antonio | |
dc.contributor.author | Sabio, José Mario | |
dc.contributor.author | Hernández Martínez, Alba | |
dc.contributor.author | Martínez Rosales, Elena | |
dc.contributor.author | Ortego Centeno, Norberto | |
dc.contributor.author | Soriano Maldonado, Alberto | |
dc.date.accessioned | 2021-05-03T08:40:36Z | |
dc.date.available | 2021-05-03T08:40:36Z | |
dc.date.issued | 2021-04-27 | |
dc.identifier.issn | 1660-4601 | |
dc.identifier.uri | http://hdl.handle.net/10835/10620 | |
dc.description.abstract | This study aimed to examine the association of relative handgrip strength (rHGS) with cardiometabolic disease risk factors in women with systemic lupus erythematosus (SLE). Methods: Seventy-seven women with SLE (mean age 43.2, SD 13.8) and clinical stability during the previous six months were included. Handgrip strength was assessed with a digital dynamometer and rHGS was defined as absolute handgrip strength (aHGS) divided by body mass index (BMI). We measured blood pressure, markers of lipid and glucose metabolism, inflammation (high sensitivity C-reactive protein [hs-CRP]), arterial stiffness (pulse wave velocity [PWV]), and renal function. A clustered cardiometabolic risk index (z-score) was computed. Results: Pearson′s bivariate correlations revealed that higher rHGS was associated with lower systolic blood pressure (SBP), triglycerides, hs-CRP, PWV, and lower clustered cardiometabolic risk (rrange = from −0.43 to −0.23; all p < 0.05). Multivariable linear regression analyses adjusted for age, disease activity (SLEDAI), and accrual damage (SDI) confirmed these results (all p < 0.05) except for triglycerides. Conclusions: The findings suggest that higher rHGS is significantly associated with lower cardiometabolic risk in women with SLE. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | autoimmune disease | es_ES |
dc.subject | cardiovascular risk | es_ES |
dc.subject | muscle strength | es_ES |
dc.subject | body mass index | es_ES |
dc.subject | metabolism | es_ES |
dc.subject | cardiovascular disease | es_ES |
dc.subject | lupus | es_ES |
dc.subject | risk factors | es_ES |
dc.title | Relative Handgrip Strength as Marker of Cardiometabolic Risk in Women with Systemic Lupus Erythematosus | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1660-4601/18/9/4630 | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | https://doi.org/10.3390/ijerph18094630 |