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The beneficial effect of statins treatment by stroke subtype
dc.contributor.author | Martínez Sánchez, Patricia | |
dc.contributor.author | Rivera Ordóñez, Carlos | |
dc.contributor.author | Fuentes, Blanca | |
dc.contributor.author | Ortega Casarrubios, María Ángeles | |
dc.contributor.author | Idrovo, Luis | |
dc.contributor.author | Díez Tejedor, Exuperio | |
dc.date.accessioned | 2024-02-05T12:22:19Z | |
dc.date.available | 2024-02-05T12:22:19Z | |
dc.date.issued | 2009-01-01 | |
dc.identifier.citation | Martínez-Sánchez P, Rivera-Ordóñez C, Fuentes B, Ortega-Casarrubios MA, Idrovo L, Díez-Tejedor E. The beneficial effect of statins treatment by stroke subtype. Eur J Neurol. 2009 Jan;16(1):127-33. doi: 10.1111/j.1468-1331.2008.02370.x. Epub 2008 Nov 25. PMID: 19049507. | es_ES |
dc.identifier.uri | http://hdl.handle.net/10835/15777 | |
dc.description.abstract | Background and purpose: Statins have shown some protective effect after ischaemic stroke in observational studies. However, this effect has never been assessed by etiological subtypes. Methods: Observational study using data from the Stroke Unit Data Bank from consecutive patients with cerebral infarction. Variables analyzed: demographic data, cardiovascular risk factors, treatment with statins at stroke onset, stroke severity, stroke subtype, in-hospital complications, length of stay, and functional status at discharge (modified Rankin Scale). Results: A total of 2742 patients were included, 1539 were men. Mean age was 69.17 years (SD 12.19). Of these, 281 patients (10.2%) were receiving statins when admitted. The logistic regression analyses showed that previous treatment with statins was an independent predictor for better outcome at discharge among all strokes (OR, 2.08; 95% CI, 1.39 to 3.1) as well as for the atherothrombotic (OR, 2.79; 95% CI, 1.33 to 5.84) and lacunar strokes (OR, 2.28; 95% CI, 1.15 to 4.52) after adjustment for demographic data, risk factors, previous treatments, stroke subtypes, stroke severity, in-hospital complications and length of stay. This benefit was not observed either in cardioembolic or in other etiology strokes. Conclusions: Previous treatment with statins is an independent factor associated with good outcomes in patients with ischaemic stroke. Atherothrombotic and small vessel strokes show the greatest benefit. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | Wiley | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | acute stroke, atherothrombotic infarction, lacunar infarction, outcome, statins | es_ES |
dc.title | The beneficial effect of statins treatment by stroke subtype | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | 10.1111/j.1468-1331.2008.02370.x |