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Young Women Have Poorer Outcomes than Men after Stroke
dc.contributor.author | Martínez-Sánchez, Patricia | |
dc.contributor.author | Fuentes, Blanca | |
dc.contributor.author | Fernández-Domínguez, Jéssica | |
dc.contributor.author | Ortega-Casarrubios, María Ángeles | |
dc.contributor.author | Aguilar-Amat, María José | |
dc.contributor.author | Abenza-Abildúa, María José | |
dc.contributor.author | Idrovo-Freire, Luis | |
dc.contributor.author | Díez-Tejedor, Exuperio | |
dc.date.accessioned | 2024-02-05T12:53:33Z | |
dc.date.available | 2024-02-05T12:53:33Z | |
dc.date.issued | 2011-02-24 | |
dc.identifier.citation | Martínez-Sánchez P, Fuentes B, Fernández-Domínguez J, Ortega-Casarrubios Mde L, Aguilar-Amar MJ, Abenza-Abildúa MJ, Idrovo-Freire L, Díez-Tejedor E. Young women have poorer outcomes than men after stroke. Cerebrovasc Dis. 2011;31(5):455-63. doi: 10.1159/000323851. Epub 2011 Feb 24. PMID: 21346351. | es_ES |
dc.identifier.issn | 1015-9770 | |
dc.identifier.uri | http://hdl.handle.net/10835/15804 | |
dc.description.abstract | Background and purpose: Gender differences in stroke outcome have not been fully assessed in young patients. Methods: We conducted an observational study of consecutive young ischemic stroke patients (≤ 50 years of age) admitted to a stroke unit (January 1999 to December 2009). Basal data, subtype of ischemic stroke, stroke severity [Canadian Neurological Scale (CNS)], length of hospital stay, inhospital complications, mortality and functional outcome at discharge [modified Rankin Scale (mRS) score] were analyzed. For stroke severity and outcome analyses, 2 age groups were established: 15-30 (very young group) and 31-50 years old (middle-aged young group). Results: A total of 310 patients were enrolled; 128 females and 182 males. The mean age was similar in women and men (41.07 ± 8.6 vs. 42.12 ± 8.2, NS). Migraine was more frequent in women, whereas arterial hypertension, hyperlipidemia, alcohol abuse, current smoking and atherothrombotic infarction were more frequent in men (p < 0.05). Females presented greater stroke severity than men [median CNS (IQR) = 8 (3.5) vs. 9 (2.5), p = 0.014] except in the very young group [median CNS (IQR) = 9 (1.8) vs. 8 (5), p = 0.022]. Female sex was a predictor of unfavorable outcomes (mRS >2) at discharge in the total sample (OR = 3.33; 95% CI = 1.41-7.84) and in the middle-aged young group (OR = 2.62; 95% CI = 1.05-6.53), adjusted by baseline data, stroke subtype, inhospital complications, length of stay and stroke severity. Conclusions: Female gender is associated with worse outcomes in adult ischemic stroke patients up to 50 years old. However, this effect is not observed in younger patients (15-30 years). | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | KARGER | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Young people, stroke Stroke, outcome Gender, stroke | es_ES |
dc.title | Young Women Have Poorer Outcomes than Men after Stroke | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | 10.1159/000323851 |