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Development of a Score to Predict the Paroxysmal Atrial Fibrillation in Stroke Patients: The Screening for Atrial Fibrillation Scale
dc.contributor.author | Amaya Pascasio, Laura | |
dc.contributor.author | Quesada López, Miguel | |
dc.contributor.author | García Torrecillas, Juan Manuel | |
dc.contributor.author | Arjona Padillo, Antonio | |
dc.contributor.author | Martínez Sánchez, Patricia | |
dc.date.accessioned | 2024-02-06T09:26:29Z | |
dc.date.available | 2024-02-06T09:26:29Z | |
dc.date.issued | 2022-07-20 | |
dc.identifier.citation | Amaya Pascasio L, Quesada López M, García-Torrecillas JM, Arjona-Padillo A, Martínez Sánchez P. Development of a Score to Predict the Paroxysmal Atrial Fibrillation in Stroke Patients: The Screening for Atrial Fibrillation Scale. Front Neurol. 2022 Jun 28;13:900582. doi: 10.3389/fneur.2022.900582. PMID: 35837230; PMCID: PMC9274122. | es_ES |
dc.identifier.issn | 1664-2295 | |
dc.identifier.uri | http://hdl.handle.net/10835/15842 | |
dc.description.abstract | Background and purpose: An individual selection of ischemic stroke patients at higher risk of atrial fibrillation (AF) might increase the diagnostic yield of prolonged cardiac monitoring and render it cost-effective. Methods: The clinical, laboratory, and brain/cardiac imaging characteristics of consecutive ischemic stroke patients without documented AF were recorded. All patients underwent at least 72 h of cardiac monitoring unless AF was diagnosed before, transthoracic echocardiogram, blood biomarkers, and intracranial vessels imaging. A predictive grading was developed by logistic regression analysis, the screening for atrial fibrillation scale (SAFE). Results: A total of 460 stroke patients were analyzed to develop the SAFE scale, a 7-items score (possible total score 0-10): age ≥ 65 years (2 points); history of chronic obstructive pulmonary disease or obstructive sleep apnea (1 point); thyroid disease (1 point); NT-proBNP ≥ 250 pg/ml (2 points); left atrial enlargement (2 points); cortical topography of stroke, including hemispheric or cerebellar cortex (1 point); and intracranial large vessel occlusion (1 point). A score = 5 identified patients with paroxysmal AF with a sensitivity of 83% and a specificity of 80%. Conclusion: Screening for atrial fibrillation scale (SAFE) is a novel and simple strategy for selecting ischemic stroke patients at higher risk of having AF who can benefit from a more thorough etiological evaluation. External validation of SAFE in a multicenter study, with a larger number of patients, is warranted. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | FRONTIERS | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | ESUS; atrial fibrillation; embolic stroke; embolic stroke of undetermined source; ischemic stroke | es_ES |
dc.title | Development of a Score to Predict the Paroxysmal Atrial Fibrillation in Stroke Patients: The Screening for Atrial Fibrillation Scale | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274122/pdf/fneur-13-900582.pdf | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | 10.3389/fneur.2022.900582 |