Protecting-Group-Free Synthesis of Cassane-Type Furan Diterpenes via a Decarboxylative Dienone−Phenol Rearrangement

dc.contributor.author	Zentar, Houda
dc.contributor.author	Arias, Fabio
dc.contributor.author	Haidour, Ali
dc.contributor.author	Alvarez-Manzaneda Roldán, Ramón Jesús
dc.contributor.author	Chahboun, Rachid
dc.contributor.author	Alvarez-Manzaneda, Enrique
dc.date.accessioned	2024-04-12T13:18:55Z
dc.date.available	2024-04-12T13:18:55Z
dc.date.issued	2018-10-29
dc.identifier.citation	Org. Lett. 2018, 20, 7007−7010	es_ES
dc.identifier.issn	1523-7060
dc.identifier.uri	http://hdl.handle.net/10835/16340
dc.description.abstract	An expeditious route to obtaining cassane-type furan diterpenes starting from (+)-sclareolide, an inexpensive commercially available natural lactone, has been achieved by using a solvent-free Diels−Alder cycloaddition and an unprecedented decarboxylative dienone−phenol rearrangement as key steps. Its applicability is showcased by the first synthesis of (5α)-vouacapane-8(14),9(11)-diene. The synthesis, which requires no protecting group, is efficient and atom- and stepeconomical (10 steps, 20% global).	es_ES
dc.language.iso	en	es_ES
dc.publisher	American Chemical Society	es_ES
dc.title	Protecting-Group-Free Synthesis of Cassane-Type Furan Diterpenes via a Decarboxylative Dienone−Phenol Rearrangement	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.relation.publisherversion	http://dx.doi.org/10.1021/acs.orglett.8b02867	es_ES
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es_ES
dc.identifier.doi	10.1021/acs.orglett.8b02867