I2–PPh3 mediated spiroannulation of unsaturated b-dicarbonyl compounds. The first synthesis of (±)-negundoin A

dc.contributor.author	Tapia, Rubén
dc.contributor.author	Cano, M. José
dc.contributor.author	Bouanou, Hanane
dc.contributor.author	Alvarez, Esteban
dc.contributor.author	Alvarez-Manzaneda Roldán, Ramón Jesús
dc.contributor.author	Chahboun, Rachid
dc.contributor.author	Alvarez-Manzaneda, Enrique
dc.date.accessioned	2024-04-12T13:28:54Z
dc.date.available	2024-04-12T13:28:54Z
dc.date.issued	2013-09-09
dc.identifier.citation	Chem. Commun., 2013, 49, 10257	es_ES
dc.identifier.issn	1359-7345
dc.identifier.uri	http://hdl.handle.net/10835/16353
dc.description.abstract	An efficient and stereoselective spiroannulation of unsaturated enols is reported. Unsaturated b-dicarbonyl compounds undergo cyclization by reaction with catalytic I2–PPh3, affording the corresponding spiro enol ether derivatives, with complete regio- and stereoselectivity, under mild conditions. Utilizing this new methodology, the first total synthesis of the anti-inflammatory diterpene negundoin A and a naturally occurring trypanocidal aldehyde is reported.	es_ES
dc.language.iso	en	es_ES
dc.publisher	Royal Society of Chemistry	es_ES
dc.title	I2–PPh3 mediated spiroannulation of unsaturated b-dicarbonyl compounds. The first synthesis of (±)-negundoin A	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.relation.publisherversion	https://pubs.rsc.org/en/content/articlelanding/2013/cc/c3cc45921g	es_ES
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es_ES
dc.identifier.doi	10.1039/c3cc45921g