Mechanical thrombectomy in patients with medical contraindications for intravenous thrombolysis: a prospective observational study
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Alonso de Leciñana, María; Martínez Sánchez, Patricia![University of Almería authority University of Almería authority](/themes/Mirage2/images/autoridades/autoridad.png)
Date
2017-11-28Abstract
Background and purpose: The present study was conducted with the objective of evaluating the safety of primary mechanical thrombectomy (MT) in patients with large vessel occlusion (LVO) stroke and comorbidities that preclude treatment with IV thrombolysis (IVT), compared with patients who received standard IVT treatment followed by MT. Secondary objectives were to analyse the recanalization rate and outcomes.
Methods: A prospective observational multicenter study (FUN-TPA) that recruited patients treated within 4.5 hours of symptom onset was performed. Treatments were IVT followed by MT if occlusion persisted, or primary MT when IVT was contraindicated. Outcome measures were procedural complications, symptomatic intracranial hemorrhage (SICH), recanalization rate, National Institutes of Health Stroke Scale (NIHSS) score at 7 days, modified Rankin Scale (mRS) score and mortality at 90 days.
Results: Of 131 patients, 21 (16%) had medical contraindications for IVT and were treated p...
Palabra/s clave
Stroke; Thrombectomy; Thrombolysis