A short route towards merosesquiterpenes with a benzoxanthene skeleton
Identifiers
Share
Metadata
Show full item recordAuthor/s
Fernández, Antonio; Alvarez, Esteban; Alvarez-Manzaneda Roldán, Ramón Jesús![University of Almería authority University of Almería authority](/themes/Mirage2/images/autoridades/autoridad.png)
Date
2014-09-03Abstract
A short synthetic sequence for the preparation of merosesquiterpenes with a benzoxanthene skeleton starting from commercial (-)-sclareol is reported. The D ring of the target compound is obtained through a Diels–Alder cycloaddition, involving a dienoldiether derived from a tricyclic α,β-enone synthesized in two steps from the starting diterpene. Utilizing this procedure, the preparation of (+)-hongoquercin A and the first synthesis of (+)-cyclospongiaquinone-1 were achieved.