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dc.contributor.authorHajji, Lazhar
dc.contributor.authorSaraiba-Bello, Cristobal
dc.contributor.authorSegovia-Torrente, Gaspar
dc.contributor.authorScalambra, Franco
dc.contributor.authorRomerosa, Antonio
dc.date.accessioned2019-11-12T09:41:19Z
dc.date.available2019-11-12T09:41:19Z
dc.date.issued2019-09-17
dc.identifier.urihttp://hdl.handle.net/10835/7253
dc.description.abstractComplexes [RuCp(Adeninate-κN9)(PTA)2] (1), [RuCp- (Guaninate-κN9)(PTA)2] (2), [RuCp(Theophyllinate-κN7)(PTA)2] (3), [RuCp(Adeninate-κN9)(PPh3)(PTA)] (4), [RuCp(Guaninate- κN9)(PPh3)(PTA)] (5) and [RuCp(Theophyllinate-κN7)(PPh3)(PTA)] (6) were synthesized and characterized by NMR spectroscopy, elemental analysis and FT-IR (PTA = 1,3,5-triaza-7-phosphaadamantane). Crystal structures of 1·H2O·3EtOH, 3·CH3COCH3 and 4·H2O were also determined by single-crystal X-ray diffraction. The antiproliferative activities of the complexes against cisplatin-sensitive T2 and cisplatin-resistant SKOV3 cell lines have also been evaluated. Theoretical studies were preformed to elucidate how the adeninate ligand is coordinated to the metal.es_ES
dc.language.isoenes_ES
dc.relationinfo:eu-repo/grantAgreement/ES/MINECO/CTQ2015-67384-R/ES/Polímeros poliheteroorganmetálicos fluorecentes solubles en agua/PPFSAes_ES
dc.sourceEur. J. Inorg. Chem. 2019, 4078–4086es_ES
dc.titleCpRu Complexes Containing Water Soluble Phosphane PTA and Natural Purines Adenine, Guanine and Theophylline: Synthesis, Characterization, and Antiproliferative Properties.es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/full/10.1002/ejic.201900677es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1002/ejic.201900677


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